Various attempts have been made in the development and evaluation of novel dosage forms which can be retained in the stomach for an extended period of time in a predetermined manner. Gastroretentive dosage forms enable prolonged and continuous input of the drug to the upper part of the gastrointestinal tract and overcome physiological adversities. In pursuit of this endeavour, different novel strategies have been undertaken for the design of several gastroretentive drug delivery systems including floating systems. Ionotropic gelation technique is a feasible approach for achieving a prolonged and predictable drug release to control the gastric residence time using the floating dosage form that can provide newer therapeutic benefits. In this review, we have focused on exploring the design considerations, various advantages and methodology of ionotropic gelation technique along with various significant research findings in the vistas of floating multiparticulate systems.