Background: Perspective of nurse, trauma patient in the hospital demand a high degree of nursing care due to severity of trauma. Trauma care is an important part of health team the role of nurse is very essential in care of traumatic patient in order to provide treatment safely and completely. Objective: To explore evidence on nurse knowledge on trauma care, as well as their practice regarding trauma care. Methods: Pub-med was searched for reviews on knowledge and practice regarding trauma care among staff nurses. Results: The accessible literature refines to get 6 qualitative studies. In this narrative review, 6 research studies supported that knowledge and practice regarding trauma care and trauma informed care. All research study suggested that if the staff nurses are having more knowledge regarding trauma care then practice is good. Conclusion: Trauma patients treated at trauma centers that manage a higher severity of trauma condition, patients have improved outcomes. Mortality and disability prevent by providing trauma care.