Maternal fatality has long been a worldwide public health paying attention, and the capability to properly identify and report maternal deceases has mostly been a defy. This paper aimed to identify the socio-demographic factors associated with maternal fatality in Juba, South Sudan using data collected from 160 pregnant women aged 15-49 years at Juba Teaching Hospital. The findings of logistic regression showed - that women’s income, estimated distance to Juba Teaching Hospital and maternal education were significantly associated with maternal fatality. The paper recommends for improve economic situation, roads and means of transport and educational chances for women.